- Mother of singer Julio Iglesias Jr., Chabeli Iglesias, Enrique Iglesias, Tamara Falcó and Ana Boyer.
- She was the third child born to her wealthy family. She is of Asian-Filipino and Spanish descent. Her paternal grandfather, Fausto Preysler, was originally from Spain, and she has other Spanish ancestors.
- She is a niece of actress Neile Adams, a half-first cousin of Neile's children, American actors Chad McQueen' and Terry McQueen, and a half-first cousin, once removed, of Chad's son, actor Steven R. McQueen. Isabel's maternal grandfather, José Salgado Arrastia, was Neile's father.
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