- Older brother of Luke Wilson and Owen Wilson.
- In The Royal Tenenbaums (2001), the hand that is seen with the BB lodged between its knuckles is not Ben Stiller's, but Andrew Wilson's.
- When they were children, Andrew and brother Owen Wilson were horsing around with a BB gun. Owen accidentally fired the gun at Andrew's hand, and the BB has been there ever since.
- Attended the all-boys' St. Mark's School of Dallas, Texas with his brothers Luke Wilson and Owen Wilson; and Tommy Lee Jones and Stephen Dignan.
- Has a son, Joseph 'Joey' Obiamiwe Wilson (born 2003).
- He is of Irish descent.
- Divorced and lives in California.
- Nephew of Joe Wilson.
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