- An accomplished juggler and skilled in circus arts.
- Discovered acting at the age of 16 while performing in a high school production of "How to Succeed in Business Without Really Trying."
- After guest-starring in two episodes of Newhart (1982), in 1984, he was brought in to replace Steven Kampmann the following year.
- Credited Bob Newhart as his favorite acting mentor/best friend.
- He is of Italian descent.
- Was originally not on the Emmy nominations list for Guest Actor in a Comedy Series in 2016 (a category which he ultimately won). He only became a nominee when original nominee Peter MacNicol was disqualified because he appeared in too many episodes of Veep (2012)'s fifth season and could no longer be categorized as "guest performer". Scolari, who won the next-highest number of votes without actually being nominated, was then moved up to be one of the six nominees.
- Dreamed of being a professional baseball player but an elbow injury ended that.
- Survived by his four children: Nicholas, Joseph, Keaton, and Cali.
- Cremated and his ashes given to his family.
- Frequently played golf with his good buddy Bob Newhart.
- In Met future wife Cathy Trien in Boston in 1996 while performing in a production of "Grease".
- Best known by the public for his role as Michael Harris on Newhart (1982) and for his starring role as Wayne Szalinski on Honey, I Shrunk the Kids: The TV Show (1997).
- Starring in Boeing, Boeing Playing Sept 20th - Nov 23rd, 2008 at Stage West Mississauga, Ontario. (October 2008)
- Starring in the new off-Broadway comedy by Kenny Solms, "It Must Be Him.". (September 2010)
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