- Many of their albums contains cryptic messages.
- Their song "Madness" was written by Matthew Bellamy as a personal reflection after a fight with girlfriend and actress Kate Hudson.
- As a band, they received an Honorary Doctorate of Arts from the University of Plymouth for their contributions to music.
- One of five musical artists to win the Grammy Award for Best Rock Album multiple times, after Sheryl Crowe, Foo Fighters, U2 and Green Day.
- As of 2016, they are ranked 5th place in having the must cumulative weeks at number one on the US Billboard Alternative Songs chart with 45 weeks total.
- Singer Matt Bellamy's father, George Bellamy, was rhythm guitarist in the 1960s pop group The Tornados, who were the first British band to have a United States number one song, with "Telstar.".
- Their song "Survival" served as the official song for the London 2012 Olympics.
- Their song "Exogenesis: Part I" from The Resistance (2009) was used by director Guy Ritchie in the Jude Law advert for Dior Homme, "A Rendezvous.".
- The instrumental song "The 2nd Law: Isolated System" from The 2nd Law is prominently featured in the opening credits of the 2013 film World War Z.
- In their native UK, they have 5 consecutive #1 albums. Their first #1 album in the United States was Drones (2015).
- English rock band.
- Some songs from their first album, released in 1999, date as far back as 1996.
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