New York, May 8 (Ians) US researchers have developed a groundbreaking new diagnostic technique that will allow for faster and more accurate detection of neurodegenerative diseases Alzheimer’s and Parkinson’s, and chronic wasting disease in animals.
Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, mad cow disease, and Cwd (widely found in deer) share a common feature — the buildup of misfolded proteins in the central nervous system. Detecting these misfolded proteins is crucial for understanding and diagnosing these devastating disorders.
However, existing diagnostic methods, like enzyme-linked immunosorbent assay and immunohistochemistry, can be expensive, time-consuming, and limiting in terms of antibody specificity.
The novel method, developed by University of Minnesota researchers, dubbed Nano-QuIC (Nanoparticle-enhanced Quaking-Induced Conversion), significantly improves the performance of advanced protein-misfolding detection methods, such as the Nih Rocky Mountain Laboratories’ Real-Time Quaking-Induced Conversion (Rt-QuIC) assay.
“Testing for these neurodegenerative diseases in both animals and humans has been a major challenge to our society,...
Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, mad cow disease, and Cwd (widely found in deer) share a common feature — the buildup of misfolded proteins in the central nervous system. Detecting these misfolded proteins is crucial for understanding and diagnosing these devastating disorders.
However, existing diagnostic methods, like enzyme-linked immunosorbent assay and immunohistochemistry, can be expensive, time-consuming, and limiting in terms of antibody specificity.
The novel method, developed by University of Minnesota researchers, dubbed Nano-QuIC (Nanoparticle-enhanced Quaking-Induced Conversion), significantly improves the performance of advanced protein-misfolding detection methods, such as the Nih Rocky Mountain Laboratories’ Real-Time Quaking-Induced Conversion (Rt-QuIC) assay.
“Testing for these neurodegenerative diseases in both animals and humans has been a major challenge to our society,...
- 5/8/2023
- by Agency News Desk
- GlamSham
Image Source: Getty / Peter Larsen
Jake Pavelka was at the forefront of one of The Bachelor's most notorious breakups - and now, he's revealing behind-the-scenes details from the show.
In case you need a refresher, Jake was the leading man on season 14. His final two women were the not-so-liked Vienna Girardi and America's sweetheart Tenley Molzahn. Ultimately, he proposed to Vienna and the two were in pure engaged bliss. Fast forward to a month in and their relationship started going downhill, and soon enough they were practically enemies. Jake was upset that Vienna ran to the tabloids about their personal relationship, but she just wanted to be heard in what was described as an emotionally abusive relationship.
In late May of this year, Jake appeared on The Ben and Ashley I Almost Famous Podcast, hosted by Bachelor alumni Ben Higgins and Ashley Iaconetti. It was there that Jake revealed some never-before-heard info.
Jake Pavelka was at the forefront of one of The Bachelor's most notorious breakups - and now, he's revealing behind-the-scenes details from the show.
In case you need a refresher, Jake was the leading man on season 14. His final two women were the not-so-liked Vienna Girardi and America's sweetheart Tenley Molzahn. Ultimately, he proposed to Vienna and the two were in pure engaged bliss. Fast forward to a month in and their relationship started going downhill, and soon enough they were practically enemies. Jake was upset that Vienna ran to the tabloids about their personal relationship, but she just wanted to be heard in what was described as an emotionally abusive relationship.
In late May of this year, Jake appeared on The Ben and Ashley I Almost Famous Podcast, hosted by Bachelor alumni Ben Higgins and Ashley Iaconetti. It was there that Jake revealed some never-before-heard info.
- 6/2/2018
- by Caitlyn Fitzpatrick
- Popsugar.com
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