Mayim Bialik, Kaley Cuoco, Johnny Galecki, Simon Helberg, Jim Parsons, Melissa Rauch, and Kunal Nayyar in The Big Bang Theory (2007)

Kaley Cuoco, Johnny Galecki, Simon Helberg, Jim Parsons, and Melissa Rauch in The Big Bang Theory (2007)

Kaley Cuoco, Johnny Galecki, Simon Helberg, Jim Parsons, and Kunal Nayyar in The Big Bang Theory (2007)

Kaley Cuoco, Johnny Galecki, and Jim Parsons in The Big Bang Theory (2007)

Alfred Molina, Sharon Lawrence, Kaley Cuoco, Alexa PenaVega, and Betty White in Ladies Man (1999)

Kaley Cuoco and Chris Messina in Shotgun Wedding (2022)

Kaley Cuoco and Tom Pelphrey in 82nd Golden Globe Awards (2025)

Kaley Cuoco and Bill Nighy in Role Play (2024)

Kaley Cuoco and David Oyelowo in Role Play (2024)

Kaley Cuoco, Chris Messina, Priscilla Quintana, and Sebastian Quinn in Based on a True Story (2023)

Kaley Cuoco and Chris Messina in Based on a True Story (2023)

Kaley Cuoco, Chris Messina, and Tom Bateman in Based on a True Story (2023)

Kaley Cuoco, Annabelle Dexter-Jones, and Aisha Alfa in Based on a True Story (2023)

Kaley Cuoco in Based on a True Story (2023)

Kaley Cuoco and Cheryl Hines in Backwards and Forwards (2022)

Kaley Cuoco and Griffin Matthews in No Exit (2022)

Kaley Cuoco, Zosia Mamet, Griffin Matthews, and Deniz Akdeniz in No Exit (2022)

Kaley Cuoco and T.R. Knight in Brothers & Sisters (2022)

Kaley Cuoco, Al Santos, Paul Wesley, and Gloria Votsis in Killer Movie (2008)

Kaley Cuoco, Al Santos, Paul Wesley, and Gloria Votsis in Midnight Movie (2008)

Caroline Rhea and Kaley Cuoco in To Be Fat Like Me (2007)

Beau Bridges, Dale Midkiff, Bradley Joseph, Kaley Cuoco, Edwin Hodge, Billy Kay, and Daniel Letterle in Debating Robert Lee (2004)

John Ritter, Katey Sagal, Kaley Cuoco, Amy Davidson, and Martin Spanjers in 8 Simple Rules (2002)