- Bob Hope referred to Best, as his comedic co-star in The Ghost Breakers (1940), as one of the finest talents he had ever worked with.
- He came to Hollywood serving as a chauffeur for a Mississippi white couple on vacation, and decided to stay and seek a career in show business.
- In his earliest film appearances, in the early 1930s, if he was given screen credit he was billed as "Sleep 'n' Eat".
- Perhaps best remembered as Algernon, the comic relief who introduces Humphrey Bogart to the bad luck dog, Pard, in Bogart's star-making role, High Sierra.
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