- Best friend was Telly Savalas, who was also daughter Jennifer Aniston's godfather.
- Father of Jennifer Aniston and Alexander Aniston (b. 1989).
- Speaks fluent Greek and Spanish.
- Served in the US Navy as an intelligence officer on active duty in Panama and later in the reserves attaining the rank of Lieutenant Commander.
- According to the DVD commentary from the first season of The Mary Tyler Moore Show (1970), he was supposed to play the role of Ted Baxter before Ted Knight was found.
- He has acted in over 40 theatrical productions including his debut in the Broadway musical "Little Mary Sunshine" and the Hollywood production of Arthur Miller's "Death of a Salesman".
- He is well known to Days of Our Lives (1965) fans as Victor Kiriakis, but years before joining the show as Victor, he auditioned for the role of Doug Williams on the series.
- Graduated from Penn State University with a BA in Theater Arts.
- Has two sisters, Mary Aniston (1929-2017) and Helen Aniston (b. 913). One brother, Gustau Aniston (1926-1937).
- Son of Anthony Aniston (1889 - 1965) and Stella "Yiayia" Joanna Aniston (1899 - 1992).
- Ex-stepfather of John T. Melick.
- Grandfather of Ryat Aniston (b. 2014) and Kira Aniston (b. 2016).
- Ex-father-in-law of Adriane Hallek and Justin Theroux.
- Former father-in-law of Brad Pitt
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