- He was forced to retire from acting due to problems with arthritis, but could still do voiceover work.
- Best known by the public for his starring role as Secret Agent John Steed on The Avengers (1961).
- Was expelled from Eton for bookmaking.
- He was born, the elder of two brothers, to a wealthy and extraordinarily eccentric English-Scottish family. In 1925, aged 3, he and his family moved to College House in Lambourn, Berkshire. As his father (Daniel Macnee), a race horse trainer, had drank and gambled the family's money away, his mother (Dorothea Mary, nee Henry; died November 29, 1984) took young Patrick to live with her female lover, Evelyn, in a huge mansion in southern England, where he wore kilts until the age of 11. He was encouraged to call his mother's partner, who paid for his schooling through Eton, as "Uncle Evelyn".
- For many years he smoked 80 cigarettes a day and drank a bottle of Scotch whisky every night. He was forced to give up drinking after being diagnosed with liver disease in the mid-1980s.
- During his run on The Avengers (1961), Macnee's only weapon was an umbrella sword; he was rarely if ever seen carrying or using a gun. Macnee has stated in interviews that he insisted on this, because he had seen enough carnage in combat during his military service in World War II.
- He is one of three main avengers (the others being Honor Blackman and Diana Rigg) to appear in a "James Bond' film. He played "Sir Godfrey Tibbett" in A View to a Kill (1985).
- He was the last surviving cast member of Hamlet (1948).
- Acting mentor and friends with Diana Rigg.
- In WWII he was a naval commander on MTB's 1942 -46.
- He was an avid nudist. Honor Blackman claimed that he once invited her to play tennis in the nude. She politely declined.
- Became a United States citizen in 1959. In addition to his acting career, Macnee worked as a television producer in Britain, the United States and Canada. He is considered to be one of the pioneers of Canadian television.
- He was a spokesperson for Sterling Motor Car Company in 1991.
- Has played the role of Algernon Moncrieff in three different television productions of Oscar Wilde's "The Importance of Being Earnest".
- Was considered for the roles of Dr. Hans Fallada, Sir Percy Heseltine and Dr. Armstrong in the science fiction horror film Lifeforce (1985).
- Played a knighted character various times; Sir Percy in Les Girls (1957), Sir John Raleigh in The Return of the Man from U.N.C.L.E.: The Fifteen Years Later Affair (1983), Sir Denis Eton-Hogg in This Is Spinal Tap (1984), Sir Godfrey Tibbett in A View to a Kill (1985), Sir Cyril Landau in Shadey (1985), Sir Geoffrey Rimbatten in Lime Street (1985), Sir Wilfred in Waxwork (1988) and Waxwork II: Lost in Time (1992), Sir Colin in The Gambler Returns: The Luck of the Draw (1991), and Sir Thomas Matthews in Family Law (1999).
- He passed away on June 25, 2015, at age 93, just 2 days after [Dick Van Patten], and within one year of three other television legends, also born in 1922, either 92 or 93: [Ellen Vogel], [Haskell Wexler] (who also shared the same birthday with Macnee) and [Lizabeth Scott].
- When asked which [The Avengers (1961)] female lead was his favorite, Macnee declined to give a specific answer, when he already provided his evaluation of the female leads.
- His parents, who were 19 years apart, Dorothea Mabel married Daniel Macnee, in June 1920, nearly 2 years before Patrick was born.
- He was cremated and his ashes were given to his daughter Jennifer.
- Was born about three months and three weeks before his fellow British actor Christopher Lee. Macnee passed on eighteen days after Lee.
- He was the only actor to appear in every episode of The Avengers (1961).
- In 1929, when young Patrick was 7, the Macnee's were separated when Daniel went to India to take up an appointment at the Bombay racecourse, while Dorothea and her son Patrick moved to live with Evelyn at Rooksnest.
- He was considered to voice Dr. Dawson in The Great Mouse Detective (1986).
- He made his acting debut with the Bradford Reportary Theatre.
- With the success of the Avengers TV series, Decca Record approached Honor Blackman and Patrick Mcnee to make a novelty record of Kinky Boots, This was fine for Honor as she had a good voice but Patrick said he was tone deaf and had no sense of rhythm which he proved at a rehearsal. Honor dragged him into a pub and plied him with brandy and told him to stop trying to sing and just speak his lines. Back at the studio the producer tapped him on the shoulder to cue him in at the right moment. The song flopped on its first release, but when it was re-released in 1990 it reached number 5.
- He trained at the Webber Douglas Academy of Dramatic Arts in London, England whose alumni include Terence Stamp, Elizabeth Knowelden, Hugh Bonneville, Rupert Friend, Antony Sher, Daniel Hunt, Matthew Goode, Sue Johnston, Minnie Driver and Julian Fellowes.
- He came down with a case of Bronchitis during his World War II service and was hospitalized when his Torpedo was sunk, killing all on board.
- He played Dr. John Watson in Sherlock Holmes in New York (1976), Sherlock Holmes and the Leading Lady (1991) and Sherlock Holmes: Incident at Victoria Falls (1992) and Sherlock Holmes in The Hound of London (1993).
- According to Edgar Lansbury's book "The Magic of Believing A Lansbury Family Memoir" 16 year old Patrick McNee played Orlando to 13 year old Angela Lansbury's Audrey in a school production of As You Like It. They would later work together in a 1958 episode of Playhouse 90 and again in two Murder She Wrote episodes.
- His favourite actors were Anthony Quayle, Paul Scofield, Robert Stephens and Michael Gambon, because of how natural they were.
- His mother left his father, who was a racehorse trainer,.
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