- She claimed that the father of her son, Caleb Goddard (born in 1970), is Jack Nicholson. In 1984, Nicholson stated that he was not convinced he is Caleb's father, but in 1996, Caleb stated that Nicholson had acknowledged him as his son.
- Has given acting classes to animation artists at Dreamworks in 1996. The training was intended to improve the realistic acting style of The Prince of Egypt (1998), the studio's first animated feature.
- Susan was raised by her great-aunt until she was 6, when her aunt died. She subsequently went back to live with her parents, but because of neglect and physical abuse, moved out at age 15 and stayed with a family in Harlem until she finished high school.
- Had a daughter (Catherine M. Curry) (born in 1968), with Steve Curry.
- Made her professional debut in Thornton Wilder's one-act play "Pullman Car Hiawatha" at a summer theater in Maryland. First appeared on the New York stage in 1965 in an Off-Broadway revival of Arthur Miller's "A View From the Bridge" with Robert Duvall and Jon Voight.
- Received a full scholarship to the Catholic University of America in Washington, where she studied music and drama.
- Was originally cast in the role of country singer Barbara Jean in Nashville (1975), but her salary requirements exceeded the ensemble film's budget; she was replaced by Ronee Blakley.
- Grduated from William Cullen Bryant High School (Queens, New York) in 1960.
- At one time, was dating rock musician Robbie Robertson of The Band.
- Her paternal grandfather was of German Jewish descent. The rest of her ancestry was Irish and English.
- Born to Renald Anspach Jr. (1918-1975), a WWII veteran and later a factory worker, and his wife Gertrude "Trudy" Kehoe (1923-1996), a secretary and singer. The couple met at the 1939 New York World's Fair.
- Three grandchildren.
- Ex-daughter-in-law of Ernie Ball.
- Reputedly an alcoholic.
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