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- CreatorAdam HorowitzEdward KitsisStarsGinnifer GoodwinJennifer MorrisonLana ParrillaA young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed.
- CreatorJustin HalpernPatrick SchumackerStarsChristopher MeloniRachael HarrisConnor BuckleyA boy becomes a man, and a man becomes a father, in a time before coming of age was something you could Google.
- CreatorMichael CrichtonStarsAnthony EdwardsGeorge ClooneyJulianna MarguliesThe doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- CreatorChris FedakJosh SchwartzStarsZachary LeviYvonne StrahovskiJoshua GomezWhen a computer geek inadvertently downloads critical government secrets into his brain, both the CIA and the NSA assign an agent to protect him and exploit his newfound skills.
- CreatorDiablo CodyStarsToni ColletteJohn CorbettRosemarie DeWittA woman struggles to find a balance between her dissociative identity disorder and raising a dysfunctional family.
- CreatorAndy BreckmanStarsTony ShalhoubJason Gray-StanfordTed LevineThe series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant while battling with an obsessive-compulsive disorder.
- CreatorMark V. OlsenWill SchefferStarsBill PaxtonJeanne TripplehornChloë SevignyA Utah polygamist who owns home improvement stores in the Salt Lake City area juggles relationships with three wives while trying to keep his complex family life from becoming a public scandal.
- CreatorGreg BerlantiMarc GuggenheimStarsJonny Lee MillerNatasha HenstridgeLoretta DevineSan Francisco lawyer Eli Stone begins to see things, which leads him to discover a brain aneurysm. But his visions lead him to accept cases with little monetary gain but a lot of moral goodness.
- CreatorPaul T. ScheuringStarsDominic PurcellWentworth MillerAmaury NolascoA structural engineer installs himself in a prison he helped design, in order to save his falsely accused brother from a death sentence by breaking themselves out from the inside.
- CreatorDavid KohanMax MutchnickStarsEric McCormackDebra MessingMegan MullallyGay lawyer Will and straight interior designer Grace share a New York City apartment. Their best friends are gleeful and proud gay Jack and charismatic, filthy-rich, amoral socialite Karen.
- CreatorCecelia AhernDonald ToddStarsChristina ApplegateJennifer EspositoKevin DunnA woman suffers from amnesia and is forced to find out who she really is.
- CreatorHank SteinbergStarsAnthony LaPagliaPoppy MontgomeryEnrique MurcianoSeries about the special FBI Missing Persons Unit (MPU) that finds missing people by applying advanced psychological profiling to reveal the victims' lives.
- CreatorBryan FullerStarsLee PaceAnna FrielChi McBrideA pastry chef with the power to bring dead people back to life solves murder mysteries with his resurrected childhood sweetheart, a cynical private investigator, and a lovesick waitress.
- CreatorStephen GallagherStarsRufus SewellMarley SheltonOmar Benson MillerA government scientist and his tough, attractive FBI handler try to save people from deadly scientific experiments, poisoners, rare diseases, and environmental hazards.
- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorDarren StarStarsSarah Jessica ParkerKim CattrallKristin DavisFour female New Yorkers gossip about their sex lives (or lack thereof) and find new ways to deal with being a woman in the late 1990s.
- CreatorAmy Sherman-PalladinoStarsLauren GrahamAlexis BledelKeiko AgenaA dramedy centering around the relationship between a thirtysomething single mother and her teen daughter living in Stars Hollow, Connecticut.
- CreatorDan LevineDeborah Joy LeVineStarsChris VanceJacqueline McKenzieMarisa RamirezThe psychiatrist seeking to save his sister as well his patients while using any means necessary.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorClaudia LonowStarsJenna ElfmanJon FosterAshley Jensen37-year-old Billie breaks up with her boss at the newspaper and gets pregnant by 22-year-old Zack, who moves into her apartment. They both have their pals.
- CreatorMeredith StiehmStarsKathryn MorrisDanny PinoJohn FinnThe Philadelphia homicide squad's lone female detective finds her calling when she is assigned "cold cases". Detective Lilly Rush combines her instincts with the updated technology to bring about justice for all the victims she can.
- CreatorKari LizerStarsJulia Louis-DreyfusClark GreggHamish LinklaterA divorced mom tries to keep pace with everyone around her.
- CreatorRobert BordenStarsBen RappaportAnisha NagarajanDiedrich BaderA manager is sent to India to oversee a staff of customer service representatives.
- StarsChris O'DowdRichard AyoadeKatherine ParkinsonThe comedic misadventures of Roy, Moss and their grifting supervisor Jen, a rag-tag team of IT support workers at a large corporation headed by a hotheaded yuppie.
- CreatorSteven LilienElizabeth SarnoffBryan WynbrandtStarsSarah JonesJorge GarciaJonny CoyneIn 1963, all the prisoners and guards mysteriously disappear from Alcatraz. In the present day, they resurface and a secret agency are tasked with re-capturing them.