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- CreatorMichael CrichtonStarsAnthony EdwardsGeorge ClooneyJulianna MarguliesThe doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- DirectorThomas SchlammeStarsAnthony EdwardsGeorge ClooneyNoah WyleWhile a film crew is filming in the ER, it's Elizabeth Corday's first day.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleJulianna MarguliesCarter mentors a talented teen from a very rough neighborhood. Romano is upset about Benton's interest in the fellowship. Lucy continues impressive work in her Psych rotation, treating a law student with homicidal impulses and an angry youngster who is being severely over-medicated. Jeanie continues to grapple with her Hepatitis-C but gets a huge boost from a kindly minister. Hathaway reveals she is pregnant after a kid kicks her in the stomach, risking her baby. Greene and Corday attempt to go to a ball for trauma physicians but end up getting lost repeatedly while having a lot of fun hanging out together.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleJulianna MarguliesThe rest of the staff finds out that Hathaway is pregnant. Benton begins a custody battle for his son when Carla Reese reveals an intention to marry Roger and take the child to Germany. Weaver rescues a toddler that has been drugged. Carter's protégé is mugged and beaten up. Greene and Corday fall in love.
- DirectorLaura InnesStarsAnthony EdwardsNoah WyleJulianna MarguliesDr. Greene and Dr. Corday bond with their parents, Lucy cares for a patient with a psychotic break, and Valentine's Day celebrations in the ER end tragically.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleJulianna MarguliesCarter and Lucy are discovered and the staff struggles to save them and go on with normal patient care.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleLaura InnesDr. Carter struggles with his drug dependency; a custodial strike leaves the ER cluttered with garbage; a riot at a high-school football game leaves several wounded.
- DirectorChristopher ChulackStarsAnthony EdwardsNoah WyleLaura InnesAbby's mother decides to stay in town; Carter attempts to find a drug addict who left the hospital: Greene discovers his health is failing.
- DirectorDavid NutterStarsAnthony EdwardsNoah WyleLaura InnesMark Green is in New York on New Years eve for cancer surgery. Meanwhile a father and son are involved in a car crash.
- DirectorMarita GrabiakStarsAnthony EdwardsNoah WyleLaura InnesA demented patient causes a shootout in the emergency room. After terrorizing people in the ER with a gun, she gets shot by a policeman. She soon dies. Benton later discover her dementia was caused by an aftereffect of his surgery that he and Cleo should have detected. Carter pursues a cute intern.
- DirectorChristopher MisianoStarsAnthony EdwardsNoah WyleLaura InnesNumerous mishaps threaten to mar Corday and Greene's wedding day. As the very pregnant Corday becomes increasingly agitated, the presence of her bickering divorced parents does little to improve her mood. With the intense rain, Greene has a difficult time making it to the church. But, evenutally, he arrives and they joyfully wed.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleLaura InnesThe ER is flooded with foster care home residents, attacked by a shooter bent on tracking down his son, who, with the help of Dr. Greene, was put into the foster care system amid allegations he was being abused by his father.
- DirectorDavid NutterStarsAnthony EdwardsNoah WyleLaura InnesWhen a torrential rainstorm pounds Chicago, patients deluge the emergency room while Weaver speeds to an accident site. There, she finds a pregnant woman, Vicki, lying injured inside a wrecked ambulance while live power lines spark. Fourth-year student Michael Gallant makes a dangerous decision in order to help.
- DirectorRichard ThorpeStarsAnthony EdwardsNoah WyleLaura InnesPeter Benton continues his court fight against Reese's stepfather, Roger, who seems to have the upper hand. When a woman is accidentally shot during a gas station robbery, Dr. Corday tries to convince the husband to let them harvest her organs. A 15 year old boxer is brought in with a head trauma after sparring with his older brother. Newlyweds are having trouble when she constantly breaks out in a rash; Carter thinks he knows the cause. Luka tells Abby that he may marry Nicole, who has told him she is pregnant. Dr. Green lays down the law when the police bring in a high school student and he learns that his daughter is outside sitting in the police car.
- DirectorNelson McCormickStarsAnthony EdwardsNoah WyleLaura InnesAn accidental overdose brings Drs. Green and Corday's baby into the ER.
- DirectorJessica YuStarsAnthony EdwardsNoah WyleLaura InnesDrs. Corday and Greene are awkward when working together in the ER. Dr. Weaver treats victims of an intense fire that may take the life of a dear friend.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleLaura InnesAs Dr. Greene's brain tumor begins affecting his coordination, he becomes concerned that his fate will be similar to the terminally ill patients he treats.
- DirectorJack OrmanStarsAnthony EdwardsNoah WyleLaura InnesDr. Carter reads a letter from terminally ill Dr. Green to the ER staff. Dr. Weaver lashes out at a mentally challenged patient. A terminal, homeless man continues asking for Dr. Green.
- DirectorJohn WellsStarsAnthony EdwardsNoah WyleLaura InnesDr. Greene's final days are spent in Hawaii with Rachel, teaching her to drive and surf. When he suffers a seizure, Elizabeth is called. Mark refuses to go home. He manages to make amends with his daughter before his eventual death.
- DirectorJonathan KaplanStarsNoah WyleLaura InnesMekhi PhiferDr. Carter, Abby and other staff of the ER are quarantined as the CDC investigate a mysterious, deadly outbreak.
- DirectorJack OrmanStarsNoah WyleLaura InnesMekhi PhiferAbby's family nightmare continues as she searches for her missing brother Eric, who she suspects is suffering from serious mental problems. Gallant accompanies her to his military base where they find Maggie, whom Eric turned to for help. When he's transferred, Abby and Maggie go to a Midwestern air force base, hoping to prevent Eric from being court-martialed for being absent without leave. Carter struggles to get out of Chicago to join Abby. Meanwhile, Corday treats a family of patients who, while building a snowman, were severely injured after being struck by a truck driver. She must help the father, Stuart, make a life-or-death decision. Corday also sympathizes with troubled surgical resident Paul Nathan as he struggles with the increasing symptoms of his physical handicap.
- DirectorAlan J. LeviStarsNoah WyleLaura InnesMekhi PhiferDr. Pratt brings a gun into the ER; Dr. Weaver tries to conceal her pregnancy; a woman plots against her dying husband; Dr. Chen treats math students who overdosed on an unknown stimulant.
- DirectorChristopher ChulackStarsNoah WyleLaura InnesMekhi PhiferOn Thanksgiving Day, a helicopter crash outside the ER leaves several injured. Alex tries to bring Sam and Luka together.
- DirectorLaura InnesStarsNoah WyleMaura TierneyMekhi PhiferAbby and Neela are assigned to a month-long rotation in the neonatal intensive care unit where they experience emotional roller coasters while caring for the sick infants.
- DirectorTawnia McKiernanStarsNoah WyleMaura TierneyMekhi PhiferWeaver rushes to the aid of her wife, Sandy Lopez, when the firefighter is severely injured while working and must now battle for her life. Frightened Weaver whispers hope to Sandy by reminding the victim of their newborn child.