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- CreatorLarry DavidJerry SeinfeldStarsJerry SeinfeldJulia Louis-DreyfusMichael RichardsThe continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorRowan AtkinsonRichard CurtisStarsRowan AtkinsonMatilda ZieglerRobin DriscollBumbling, childlike Mr. Bean has trouble completing the simplest of day-to-day tasks, but his perseverance and resourcefulness frequently allow him to find ingenious ways around problems.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorEric KripkeStarsJared PadaleckiJensen AcklesJim BeaverTwo brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- CreatorPaul T. ScheuringStarsDominic PurcellWentworth MillerAmaury NolascoA structural engineer installs himself in a prison he helped design, in order to save his falsely accused brother from a death sentence by breaking themselves out from the inside.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorMark BrazillBonnie TurnerTerry TurnerStarsTopher GraceLaura PreponMila KunisA comedy revolving around a group of teenage friends, their mishaps, and their coming of age, set in 1970s Wisconsin.
- CreatorJoss WhedonStarsSarah Michelle GellarNicholas BrendonAlyson HanniganA young woman, destined to slay vampires, demons and other infernal creatures, deals with her life fighting evil, with the help of her friends.
- CreatorDavid AngellPeter CaseyDavid LeeStarsKelsey GrammerJane LeevesDavid Hyde PierceDr. Frasier Crane moves back to his hometown of Seattle, where he lives with his father and works as a radio psychiatrist.
- CreatorGregory Thomas GarciaStarsJason LeeEthan SupleeJaime PresslyA ne'er do well wins $100,000 in the lottery and decides to right all the wrongs from his past with his newfound realization!
- CreatorDonald P. BellisarioStarsScott BakulaDean StockwellDeborah PrattDuring an experiment into time travel, a scientist finds himself trapped in the past, "leaping" into the lives of different people, sorting out their problems and changing history in hopes of getting back to his own life in the present.
- CreatorDavid GreenwaltJoss WhedonStarsDavid BoreanazCharisma CarpenterAlexis DenisofThe vampire Angel, cursed with a soul, moves to Los Angeles and aids people with supernatural-related problems while questing for his own redemption.
- CreatorTina FeyStarsTina FeyAlec BaldwinTracy MorganLiz Lemon, head writer of the sketch-comedy show "TGS with Tracy Jordan", must deal with an arrogant new boss and a crazy new star while trying to run a successful television show without losing her mind.
- CreatorHart HansonStarsEmily DeschanelDavid BoreanazMichaela ConlinF.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.
- CreatorLinwood BoomerMichael GloubermanGary MurphyStarsFrankie MunizBryan CranstonJustin BerfieldA gifted young teen tries to survive life with his dimwitted, dysfunctional family.
- CreatorMichael JacobsApril KellyStarsBen SavageRider StrongWilliam DanielsAn adolescent with two siblings tests his various theories about life as he endures the trials of growing up alongside a good friend.
- CreatorAndy BorowitzSusan BorowitzStarsWill SmithJames AveryAlfonso RibeiroA streetwise, poor young man from Philadelphia is sent by his mother to live with his aunt, uncle and cousins in their Bel-Air mansion.
- CreatorJulie PlecKevin WilliamsonStarsNina DobrevPaul WesleyIan SomerhalderThe lives, loves, dangers and disasters in the town, Mystic Falls, Virginia. Creatures of unspeakable horror lurk beneath this town as a teenage girl is suddenly torn between two vampire brothers.
- CreatorAndy BreckmanStarsTony ShalhoubJason Gray-StanfordTed LevineThe series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant while battling with an obsessive-compulsive disorder.
- CreatorBonnie TurnerTerry TurnerStarsJohn LithgowJane CurtinKristen JohnstonA group of aliens is sent to Earth, disguised as a human family, to experience and report life on the third planet from the sun.
- CreatorDavid LittMichael J. WeithornStarsKevin JamesLeah ReminiJerry StillerDeliveryman Doug Heffernan has a good life: He has a pretty wife (Carrie), a big television, and friends with which to watch it. Then Carrie's goofy, annoying father Arthur moves in with them.
- CreatorJon Harmon FeldmanStarsEliza DushkuShawn ReavesZach GalifianakisA university graduate working in the city morgue is able to repeat the same day over again to prevent murders or other disasters.