The shot of Eddie biting Fraser's pant leg was actually performed by Enzo, Moose's son, who began doing stunt work for the show this season. Enzo would take over entirely for Moose in Season 8.
Per the title, "Primum non nocere" is Latin for "First, not to harm" which is a principal precept taught to all medical students.
Five years earlier (1993) on Seinfeld, Teri Hatcher, playing Jerry's girlfriend, uttered the famous line "They're real, and they're spectacular."