Some of the background character puppets for this adult puppet sitcom were reused from the children's puppet video The Adventures of Timmy the Tooth (1995).
Throughout the episodes, Greg's eyes change from buttons to actual eyes. The first episodes were filmed with button-eyes but because the episodes are shown out-of-order, the types of eyes alternate.
Greg the Bunny first appeared on a New York City public access show called "Junktape." He was then the star of interstitial short films and features on The Independent Film Channel for two years, under the show title "The Greg The Bunny Show."
Thirteen episodes were made but only 11 episodes aired. The two unaired episodes were included on the DVD.