Considering the part of Ethan Edwards to be the best character that he ever portrayed on-screen and The Searchers (1956) to be his favorite film role, John Wayne named his youngest son Ethan Wayne in homage.
Beulah Archuletta (Look) was found crying in one of the tipis by John Wayne in between shooting scenes. When Wayne asked her why she was crying, she responded that she was going to miss her son's wedding because she was filming her scenes at the time. Wayne stopped production of the film for a few days and flew her to California so that she could attend the wedding.
The eccentric character of Mose Harper, played by Hank Worden, is loosely based on an actual historical personage called Mad Mose, a legendary half-crazy Indian fighter of the American southwest with a fondness for rocking chairs.
During filming, a Navajo child became seriously ill with pneumonia and needed urgent medical attention. John Wayne had his own airplane on location and had his pilot take the little girl to a hospital. For his deed, the Navajos named him "The Man With The Big Eagle".
Natalie Wood was still a student in high school when this film was being made, and, on several occasions, John Wayne and Jeffrey Hunter had to pick her up at school. This caused a good deal of excitement among Wood's female classmates.