Joan Crawford turns in one of her best performances as a mentally disturbed woman in love with Van Heflin but married to Raymond Massey. She's found wandering the streets at the start of the film. At the hospital, she tells the film's story to doctors through a series of flashbacks. After winning an Oscar for Mildred Pierce, it seems obvious Joan wanted badly to win another. So she followed a formula that is still being followed by actors today. If you want to be recognized by your peers, play someone with an alcohol or drug problem (Humoresque -- check!) or play someone who is mentally ill (Possessed -- check!). Joan did receive an Oscar nomination for this role but didn't win.
The rest of the cast is fine. Raymond Massey is solid as her husband but it isn't one of his better roles. Geraldine Brooks is lovely in her film debut. Van Heflin plays the object of Joan's obsession. He's a thoroughly unlikable character. Heflin does fine in the part but I couldn't help wondering if the movie expected me to feel sympathy for this guy or what because he was a jerk and a cradle robber. The film is a little overlong and drags a little in the middle when Joan is acting her most normal. This is not related to Joan's other movie titled Possessed from 1931. That film was a soaper with Clark Gable.